Infectious diseases vary by geographic region and population, and they change over time. When moving from one region to another, humans are exposed to a variety of potential pathogens and also serve as part of the global dispersal process. Microbes picked up at one time and in one place may manifest in disease (and potentially be transmitted) far away in time and place. Because many microbes have the capacity to persist in the human host for months, years or even decades, the relevant time frame for study of geographic exposures becomes a lifetime. Furthermore, microbes also move and change and reach humans via multiple channels.
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