This article retrospectively examines the factors which caused Guinea Worm Disease (Dracunculiasis) to spread to epidemic levels, so as to serve as the basis for formulating a national preventive agenda to reinforce the preventive measures which have been put in place to prevent the disease from re-emerging. The hybrid conceptual framework of disease diffusion and disease ecology was used. The mixed method research design was used to collect data from a total of 11 administrative districts. Primary data was obtained from a total of 860 respondents. To achieve a representative distribution of respondents, they were proportionately selected with respect to the populations of their respective districts. A key Informant interview was conducted.
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